Unpredictability of deception in compliance with physician-prescribed bronchodilator inhaler use in a clinical trial.

@article{Simmons2000UnpredictabilityOD,
  title={Unpredictability of deception in compliance with physician-prescribed bronchodilator inhaler use in a clinical trial.},
  author={Michael Scott Simmons and Mitchell A Nides and Cynthia S. Rand and Robert A. Wise and Donald P Tashkin},
  journal={Chest},
  year={2000},
  volume={118 2},
  pages={290-5}
}
OBJECTIVE To identify subject characteristics that may be predictive of intentional dumping of metered-dose inhalers (MDIs) during a clinical trial. DESIGN Nebulizer Chronologs (NCs; Medtrac Technologies; Lakewood, CO), which record the date and time of each MDI actuation, were attached to the MDIs of participants who were given a prescribed medication schedule to follow in a clinical trial. Participants were not informed of the function of the NC or that their medication use was being… CONTINUE READING

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