Unprecedented rate enhancements of hydrogen-atom transfer to a manganese(V)-oxo corrolazine complex.

@article{Prokop2010UnprecedentedRE,
  title={Unprecedented rate enhancements of hydrogen-atom transfer to a manganese(V)-oxo corrolazine complex.},
  author={Katharine A Prokop and Sam P de Visser and David P Goldberg},
  journal={Angewandte Chemie},
  year={2010},
  volume={49 30},
  pages={5091-5}
}
The reactivity of high-valent metal–oxo species is critical to the functioning of a large class of metalloenzymes. In heme enzymes, the identity of the proximal ligand is believed to have an important effect on the generation, stability, and substrate reactivity of these intermediates. For example, the proximal cysteinate ligand in cytochrome P450 (Cyt-P450) has been suggested to increase the oxidizing power of the enzyme toward hydrocarbon (C H) substrates by enhancing the basicity (i.e. the… CONTINUE READING
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An Introduction to Chemical Kinetics

  • M. R. Wright
  • 2004
1 Excerpt

Chem

  • G. C. Yin, A. M. Danby, +4 authors J. Am
  • Soc. 2007, 129, 1512 –
  • 1513

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