Unnatural Amino Acids

@inproceedings{Pollegioni2012UnnaturalAA,
  title={Unnatural Amino Acids},
  author={L. Pollegioni and S. Servi},
  booktitle={Methods in Molecular Biology},
  year={2012}
}
  • L. Pollegioni, S. Servi
  • Published in Methods in Molecular Biology 2012
  • Chemistry
  • Ammonia-lyases catalyze a wide range of processes leading to , -unsaturated compounds by elimination of ammonia. In this chapter, ammonia-lyases are reviewed with major emphasis on their synthetic applications in stereoselective preparation of unnatural amino acids. Besides the synthesis of various unnatural -amino acids with the aid of phenylalanine ammonia-lyases (PALs) utilizing the 3,5-dihydro5-methylidene-4H-imidazol-4-one (MIO) prosthetic groups, the biotransformations leading to various… CONTINUE READING

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