Unmyelinated trigeminal pathways as assessed by laser stimuli in humans.

@article{Cruccu2003UnmyelinatedTP,
  title={Unmyelinated trigeminal pathways as assessed by laser stimuli in humans.},
  author={Giorgio Cruccu and Elizabeth Pennisi and Andrea Truini and Gian Domenico Iannetti and Antonietta Romaniello and Domenica Le Pera and Liala de Armas and Massimo Leandri and Mario Manfredi and Massimiliano Valeriani},
  journal={Brain : a journal of neurology},
  year={2003},
  volume={126 Pt 10},
  pages={
          2246-56
        }
}
Laser pulses excite superficial free nerve endings innervated by small-myelinated (Adelta) and unmyelinated (C) fibres. Whereas laser-evoked scalp potentials (LEPs) are now reliably used to assess function of the Adelta-fibre nociceptive pathways in patients with peripheral or central lesions, the selective activation of C-fibre receptors and recording of the related brain potentials remain difficult. To investigate trigeminal C-fibre function, we directed laser pulses to the facial skin and… CONTINUE READING
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