Unmasking the causes of multifactorial disorders: OXPHOS differences between mitochondrial haplogroups.

Abstract

Many epidemiologic studies have associated human mitochondrial haplogroups to rare mitochondrial diseases like Leber's hereditary optic neuropathy or to more common age-linked disorders such as Parkinson's disease. However, cellular, biochemical and molecular-genetic evidence that is able to explain these associations is very scarce. The etiology of… (More)
DOI: 10.1093/hmg/ddq246

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Cite this paper

@article{GomezDuran2010UnmaskingTC, title={Unmasking the causes of multifactorial disorders: OXPHOS differences between mitochondrial haplogroups.}, author={Aurora Gomez-Duran and David Pacheu-Grau and Esther L{\'o}pez-Gallardo and Carmen D{\'i}ez-S{\'a}nchez and Julio Montoya and Manuel Jos{\'e} L{\'o}pez-P{\'e}rez and Eduardo Ruiz-Pesini}, journal={Human molecular genetics}, year={2010}, volume={19 17}, pages={3343-53} }