Unkempt Is Negatively Regulated by mTOR and Uncouples Neuronal Differentiation from Growth Control

@inproceedings{AvetRochex2014UnkemptIN,
  title={Unkempt Is Negatively Regulated by mTOR and Uncouples Neuronal Differentiation from Growth Control},
  author={Am{\'e}lie Avet-Rochex and Nancy Carvajal and Christina P. Christoforou and Kelvin Yeung and Katja T. Maierbrugger and Carl Hobbs and Giovanna Lalli and Umut Cagin and C{\'e}dric Plachot and Helen McNeill and Joseph M. Bateman},
  booktitle={PLoS genetics},
  year={2014}
}
Neuronal differentiation is exquisitely controlled both spatially and temporally during nervous system development. Defects in the spatiotemporal control of neurogenesis cause incorrect formation of neural networks and lead to neurological disorders such as epilepsy and autism. The mTOR kinase integrates signals from mitogens, nutrients and energy levels to… CONTINUE READING