University of Groningen Intraventricular GLP-1 reduces short-but not long-term food intake or body weight in lean and obese rats

Abstract

Ž . Ž . Ž . Glucagon-like-peptide-1 7–36 amide GLP-1 , when infused into the third ventricle IVT , reduces short-term food intake. In the present experiments, we assessed whether IVT administration of GLP-1 could influence long-term food intake and body weight of lean Ž . Long Evans rats and of fatty Zucker farfa rats. In Experiment 1, we replicated the… (More)

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