University of Groningen Differential role of the 5-HT 1 A receptor in aggressive and non-aggressive mice

@inproceedings{Boer2017UniversityOG,
  title={University of Groningen Differential role of the 5-HT 1 A receptor in aggressive and non-aggressive mice},
  author={Sietse F. de Boer and Jaap M. Koolhaas},
  year={2017}
}
Differential role of the 5-HT1A receptor in aggressive and non-aggressive mice: an across-strain comparison. PHYSIOL BEHAV 00(0) 000000, 2006. According to the serotonin (5-HT)-deficiency hypothesis of aggression, highly aggressive individuals are characterized by low brain 5HT neurotransmission. Key regulatory mechanisms acting on the serotonergic neuron involve the activation of the somatodendritic inhibitory 5HT1A autoreceptor (short feedback loop) and/or the activation of postsynaptic 5… CONTINUE READING