Universal trees based on large combined protein sequence data sets

  title={Universal trees based on large combined protein sequence data sets},
  author={James R. Brown and Christophe Jean Douady and Michael J. Italia and William Marshall and Michael J. Stanhope},
  journal={Nature Genetics},
Universal trees of life based on small-subunit (SSU) ribosomal RNA (rRNA) support the separate mono/holophyly of the domains Archaea (archaebacteria), Bacteria (eubacteria) and Eucarya (eukaryotes) and the placement of extreme thermophiles at the base of the Bacteria. The concept of universal tree reconstruction recently has been upset by protein trees that show intermixing of species from different domains. Such tree topologies have been attributed to either extensive horizontal gene transfer… CONTINUE READING
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