Universal sensing by transduction of antibody binding with backscattering interferometry.

Abstract

Antibodies are the most widely used agents for biomolecular recognition because of their combination of high affinity, high specificity, broad range of compatible analytes, and commercial availability. For analytical purposes, the antibody binding event must be converted to a detectable signal; several methods are commonly employed for this. ELISA-type… (More)
DOI: 10.1002/cbic.201000671

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