Universal relationship in gene-expression changes for cells in steady-growth state

@article{Kaneko2014UniversalRI,
  title={Universal relationship in gene-expression changes for cells in steady-growth state},
  author={Kunihiko Kaneko and Chikara Furusawa and Tetsuya Yomo},
  journal={arXiv: Cell Behavior},
  year={2014}
}
Cells adapt to different conditions by altering a vast number of components, which is measurable using transcriptome analysis. Given that a cell undergoing steady growth is constrained to sustain each of its internal components, the abundance of all the components in the cell has to be roughly doubled during each cell division event. From this steady-growth constraint, expression of all genes is shown to change along a one-parameter curve in the state space in response to the environmental… 

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