Universal protein fluctuations in populations of microorganisms.

@article{Salman2012UniversalPF,
  title={Universal protein fluctuations in populations of microorganisms.},
  author={Hanna Salman and Naama Brenner and Chih-kuan Tung and Noa Elyahu and Elad Stolovicki and Lindsay S. Moore and Albert Libchaber and Erez Braun},
  journal={Physical review letters},
  year={2012},
  volume={108 23},
  pages={238105}
}
The copy number of any protein fluctuates among cells in a population; characterizing and understanding these fluctuations is a fundamental problem in biophysics. We show here that protein distributions measured under a broad range of biological realizations collapse to a single non-gaussian curve under scaling by the first two moments. Moreover, in all experiments the variance is found to depend quadratically on the mean, showing that a single degree of freedom determines the entire… CONTINUE READING
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