Universal prestorage leukoreduction in Canada decreases platelet alloimmunization and refractoriness.

@article{Seftel2004UniversalPL,
  title={Universal prestorage leukoreduction in Canada decreases platelet alloimmunization and refractoriness.},
  author={Matthew D. Seftel and Gershon H. Growe and Tanya Petraszko and W Barrett Benny and Alan Le and C Lee and John Spinelli and Heather J. Sutherland and Peter H Tsang and Donna Hogge},
  journal={Blood},
  year={2004},
  volume={103 1},
  pages={333-9}
}
Randomized controlled trials have shown a reduction in platelet alloimmunization and refractoriness in patients with acute leukemia (AL) with the use of poststorage leukoreduction of blood products. Universal prestorage leukoreduction (ULR) of red cell and platelet products has been performed in Canada since August 1999. We conducted a retrospective analysis of 13 902 platelet transfusions in 617 patients undergoing chemotherapy (CT) for AL or stem cell transplantation (SCT) before (n = 315… CONTINUE READING