Universal microfluidic gradient generator.

  title={Universal microfluidic gradient generator.},
  author={Daniel Irimia and Dan A Geba and Mehmet Toner},
  journal={Analytical chemistry},
  volume={78 10},
The study of cellular responses to chemical gradients in vitro would greatly benefit from experimental systems that can generate precise and stable gradients comparable to chemical nonhomogeneities occurring in vivo. Recently, microfluidic devices have been demonstrated for linear gradient generation for biological applications with unmatched accuracy and stability. However, no systematic approach exists at this time for generating other gradients of target spatial configuration. Here we… CONTINUE READING

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