Universal kinetics for engagement of mechanosensing pathways in cell adhesion

Abstract

When plated onto substrates, cell morphology and even stem cell differentiation are influenced by the stiffness of their environment. Stiffer substrates give strongly spread (eventually polarized) cells with strong focal adhesions, and stress fibers; very soft substrates give a less developed cytoskeleton, and much lower cell spreading. The kinetics of this… (More)

Topics

7 Figures and Tables

Slides referencing similar topics