Universal database search tool for proteomics

@inproceedings{Kim2014UniversalDS,
  title={Universal database search tool for proteomics},
  author={Seong Keun Kim and Pavel A. Pevzner},
  booktitle={Nature communications},
  year={2014}
}
Mass spectrometry (MS) instruments and experimental protocols are rapidly advancing, but the software tools to analyse tandem mass spectra are lagging behind. We present a database search tool MS-GF+ that is sensitive (it identifies more peptides than most other database search tools) and universal (it works well for diverse types of spectra, different configurations of MS instruments and different experimental protocols). We benchmark MS-GF+ using diverse spectral data sets: (i) spectra of… CONTINUE READING
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