Universal RNA-degrading enzymes in Archaea: Prevalence, activities and functions of β-CASP ribonucleases.

@article{ClouetdOrval2015UniversalRE,
  title={Universal RNA-degrading enzymes in Archaea: Prevalence, activities and functions of β-CASP ribonucleases.},
  author={B{\'e}atrice Clouet-d'Orval and Duy Khanh Phung and Petra S. Langendijk-Genevaux and Yves Quentin},
  journal={Biochimie},
  year={2015},
  volume={118},
  pages={278-85}
}
β-CASP ribonucleases are widespread in all three domains of life. They catalyse both 5'-3' exoribonucleolytic RNA trimming and/or endoribonucleolytic RNA cleavage using a unique active site coordinated by two zinc ions. These fascinating enzymes have a key role in 3' end processing in Eukarya and in RNA decay and ribosomal RNA maturation in Bacteria. The recent recognition of β-CASP ribonucleases as major players in Archaea is an important contribution towards identifying RNA-degrading enzymes… CONTINUE READING

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