Universal Panel Testing of Pancreatic Cancer Cases for Cancer Predisposition

@inproceedings{Young2017UniversalPT,
  title={Universal Panel Testing of Pancreatic Cancer Cases for Cancer Predisposition},
  author={Erin L Young and Bryony A Thompson and Deborah W Neklason and Angela Kathleen Snow and Matthew A Firpo and Theresa L Werner and Russell Bell and Nykole R. Sutherland and K. Robert Smith and Justin Berger and Archibald Fraser and Amanda Dawn Gammon and Cathryn Koptiuch and Wendy K. Kohlmann and Leigh A. Neumayer and David E. Goldgar and Sean J. Mulvihill and Lisa Anne Cannon Albright and Sean V. Tavtigian},
  year={2017}
}
ABSTRACT Background and Aims Genes associated with hereditary breast and ovarian cancer (HBOC) and colorectal cancer (CRC) susceptibility have been shown to play a role in pancreatic cancer susceptibility. Germline genetic testing of pancreatic cancer cases could be beneficial for at-risk relatives with pathogenic variants in established HBOC and CRC genes, but it is unclear what proportion of pancreatic cancer cases harbor pathogenic variants in these genes. Methods 66 pancreatic cancer cases… CONTINUE READING
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