The Emergence of the Omicron (B.1.1.529) SARS-CoV-2 Variant: What is the Impact on the Continued Pandemic?
- BiologyJournal of epidemiology and global health
There is emerging evidence to conclude that the Omicron variant spreading speed is much faster than the Delta and other previous variants, with the doubling time of only 2–3 days.
The Concept of Classical Herd Immunity May Not Apply to COVID-19
- MedicineThe Journal of infectious diseases
There has been speculation about when in the coronavirus disease 2019 (COVID19) pandemic we will be able to live with the virus in a manner that does not disrupt most peoples’ lives. Much of this…
A Pan-Coronavirus Vaccine Candidate: Nine Amino Acid Substitutions in the ORF1ab Gene Attenuate 99% of 365 Unique Coronaviruses: A Comparative Effectiveness Research Study
A new vaccine candidate that appears to attenuate the SARS-Cov-2 coronavirus variants to render it safe to use as a vaccine is proposed, and results indicate it may be efficacious against 99% of 365 coronaviruses.
A new day for human challenge trials?
- MedicineTrends in Molecular Medicine
Booster Vaccination to Reduce SARS-CoV-2 Transmission and Infection.
Although Spitzer et al initially aimed to provide a booster vaccine dose only for persons with antibody titers less than the median, universal boosting was recommended by health authorities and enrolled a cohort of health care workers.
Breakthrough infections after COVID-19 vaccination: Insights, perspectives and challenges
- Medicine, BiologyMetabolism Open
CD4+ T-cells from COVID-19 mRNA vaccine recipients recognize a conserved epitope present in diverse coronaviruses.
- BiologyThe Journal of clinical investigation
The hypothesis that the current mRNA vaccines elicit T cell responses that can cross-recognize bat coronaviruses and thus might induce some protection against potential zoonotic outbreaks is supported.
Coronavirus Vaccination and Mortality in the Omicron Outbreak in Iran: Mortality Reduction due to Attenuated Pathogenicity and Booster Vaccine Doses
- MedicineAvicenna Journal of Medical Biotechnology
The article's abstract is not available because the author does not have time to devote to this research.
Distinct Core Glycan and O-Glycoform Utilization of SARS-CoV-2 Omicron Variant Spike Protein RBD Revealed by Top-Down Mass Spectrometry
The findings reveal high resolution detail of Omicron O-glycoforms and their utilization to provide direct molecular evidence of proteoform alterations in the Omicrons variant which could shed light on how this variant escapes immunological protection.