Uniting the classification of cultured and uncultured bacteria and archaea using 16S rRNA gene sequences

@article{Yarza2014UnitingTC,
  title={Uniting the classification of cultured and uncultured bacteria and archaea using 16S rRNA gene sequences},
  author={P. Yarza and Pelin Yilmaz and Elmar Pruesse and F. Gl{\"o}ckner and W. Ludwig and K. Schleifer and W. Whitman and J. Euz{\'e}by and R. Amann and R. Rossell{\'o}-M{\'o}ra},
  journal={Nature Reviews Microbiology},
  year={2014},
  volume={12},
  pages={635-645}
}
Publicly available sequence databases of the small subunit ribosomal RNA gene, also known as 16S rRNA in bacteria and archaea, are growing rapidly, and the number of entries currently exceeds 4 million. However, a unified classification and nomenclature framework for all bacteria and archaea does not yet exist. In this Analysis article, we propose rational taxonomic boundaries for high taxa of bacteria and archaea on the basis of 16S rRNA gene sequence identities and suggest a rationale for the… Expand
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High proportions of bacteria and archaea across most biomes remain uncultured
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