Unique response pathways are established by allosteric interactions among nuclear hormone receptors

Abstract

Heterodimerization is a common paradigm among eukaryotic transcription factors. The 9-cis retinoic acid receptor (RXR) serves as a common heterodimerization partner for several nuclear receptors, including the thyroid hormone receptor (T3R) and retinoic acid receptor (RAR). This raises the question as to whether these complexes possess dual hormonal… (More)
DOI: 10.1016/0092-8674(95)90075-6

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