Unique properties of a second human herpesvirus 8-encoded interferon regulatory factor (vIRF-2).

@article{Bursek1999UniquePO,
  title={Unique properties of a second human herpesvirus 8-encoded interferon regulatory factor (vIRF-2).},
  author={L Bur{\'y}sek and W S Yeow and P. M. Pitha},
  journal={Journal of human virology},
  year={1999},
  volume={2 1},
  pages={19-32}
}
OBJECTIVE Human herpesvirus 8/Kaposi's sarcoma herpesvirus (HHV-8/KSHV) contains, in addition to genes required for viral replication, an unique set of nonstructural genes which may be part of viral mimicry and contribute to viral replication and pathogenesis in vivo. Among these, HHV-8 encodes four open reading frames (ORFs) that show homology to the transcription factors of the interferon regulatory factor (IRF) family. In this study we demonstrate that one of these ORFs (vIRF-2) encodes a… CONTINUE READING
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