Unique phenotype of human uterine NK cells and their regulation by endogenous TGF-beta.

@article{Eriksson2004UniquePO,
  title={Unique phenotype of human uterine NK cells and their regulation by endogenous TGF-beta.},
  author={Mikael Eriksson and Sarah K. Meadows and Charles R Wira and Charles L. Sentman},
  journal={Journal of leukocyte biology},
  year={2004},
  volume={76 3},
  pages={667-75}
}
Natural killer (NK) cells are a major population of lymphocytes in the human endometrium (EM), and NK cells can be a significant source of cytokines that alter local immune responses. The aim of this study was to determine the expression of NK cell receptors in situ and to test whether uterine NK (uNK) cells produce cytokines and how this activity may be regulated by transforming growth factor-beta (TGF-beta). We observed that human uNK cells were CD56+, CD3-, CD57-, CD9+, CD94+, killer… CONTINUE READING
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