Unique microRNA molecular profiles in lung cancer diagnosis and prognosis.

@article{Yanaihara2006UniqueMM,
  title={Unique microRNA molecular profiles in lung cancer diagnosis and prognosis.},
  author={Nozomu Yanaihara and Natasha J. Caplen and Elise D. Bowman and Masahiro Seike and Kensuke Kumamoto and Ming Yi and Robert M. Stephens and Aikou Okamoto and Jun Yokota and Tadao Tanaka and George A. Calin and Chang-gong Liu and Carlo M Croce and Curtis C. Harris},
  journal={Cancer cell},
  year={2006},
  volume={9 3},
  pages={
          189-98
        }
}
MicroRNA (miRNA) expression profiles for lung cancers were examined to investigate miRNA's involvement in lung carcinogenesis. miRNA microarray analysis identified statistical unique profiles, which could discriminate lung cancers from noncancerous lung tissues as well as molecular signatures that differ in tumor histology. miRNA expression profiles correlated with survival of lung adenocarcinomas, including those classified as disease stage I. High hsa-mir-155 and low hsa-let-7a-2 expression… CONTINUE READING
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