Unique genome-wide transcriptome profiles of chicken macrophages exposed to Salmonella-derived endotoxin

@inproceedings{Ciraci2010UniqueGT,
  title={Unique genome-wide transcriptome profiles of chicken macrophages exposed to Salmonella-derived endotoxin},
  author={Ceren Ciraci and Christopher K. Tuggle and Michael J. Wannemuehler and Dan Nettleton and Susan J. Lamont},
  booktitle={BMC Genomics},
  year={2010}
}
Macrophages play essential roles in both innate and adaptive immune responses. Bacteria require endotoxin, a complex lipopolysaccharide, for outer membrane permeability and the host interprets endotoxin as a signal to initiate an innate immune response. The focus of this study is kinetic and global transcriptional analysis of the chicken macrophage response to in vitro stimulation with endotoxin from Salmonella typhimurium-798. The 38535-probeset Affymetrix GeneChip Chicken Genome array was… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 25 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 46 references

Gene expression profiling of avian macrophage activation.

Veterinary immunology and immunopathology • 2005
View 4 Excerpts
Highly Influenced

Estimating the number of true null hypotheses from a histogram of p-values. Journal of Agricultural, Biological, and Environmental Statistics 2006, 11:337-356

D Nettleton, JTG Hwang, RA Caldo, RP Wise
BMC Genomics • 2010

Similar Papers

Loading similar papers…