Unique features of memory T cells in HIV elite controllers: a systems biology perspective.

@article{Fonseca2011UniqueFO,
  title={Unique features of memory T cells in HIV elite controllers: a systems biology perspective.},
  author={Simone Gonçalves Fonseca and Francesco Andrea Procopio and Jean-Philippe Goulet and Bader Yassine-Diab and Petronela Ancuta and Rafick Pierre S{\'e}kaly},
  journal={Current opinion in HIV and AIDS},
  year={2011},
  volume={6 3},
  pages={188-96}
}
PURPOSE OF REVIEW Elite controllers constitute a rare group of HIV-infected individuals who control HIV replication and maintain normal CD4 cell counts without antiretroviral therapy (ART). The mechanisms involved in the control of infection are poorly understood. This review will focus on the identification of signaling pathways upregulated or downregulated in different memory T-cell subsets in elite controllers by using systems biology approaches. Features of memory T cells in simian… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 93 references

HIV - 1specific interleukin21 þ CD 4 þ T cell responses contribute to durable viral control through the modulation of HIVspecific CD 8 þ T cell function

  • MF Chevalier, B Julg, A Pyo
  • J Virol
  • 2011

IL - 7dependent STAT5 activation and CD 8 þ T cell proliferation are impaired in HIV infection

  • A Vranjkovic, AM Crawley, A Patey, JB Angel
  • J Leukoc Biol
  • 2010

Interleukin - 21producing HIV1specific CD 8 T cells are preferentially seen in elite controllers

  • LD Williams, A Bansal, S Sabbaj
  • J Virol
  • 2010

Similar Papers

Loading similar papers…