Unique features of memory T cells in HIV elite controllers: a systems biology perspective.

  title={Unique features of memory T cells in HIV elite controllers: a systems biology perspective.},
  author={Simone Gonçalves Fonseca and Francesco Andrea Procopio and Jean-Philippe Goulet and Bader Yassine-Diab and Petronela Ancuta and Rafick Pierre S{\'e}kaly},
  journal={Current opinion in HIV and AIDS},
  volume={6 3},
PURPOSE OF REVIEW Elite controllers constitute a rare group of HIV-infected individuals who control HIV replication and maintain normal CD4 cell counts without antiretroviral therapy (ART). The mechanisms involved in the control of infection are poorly understood. This review will focus on the identification of signaling pathways upregulated or downregulated in different memory T-cell subsets in elite controllers by using systems biology approaches. Features of memory T cells in simian… CONTINUE READING


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