Unique and shared features of Golgi complex autoantigens.


Here we summarize recent advances in the characterization of autoimmune antigens associated with the Golgi complex. All Golgi autoantigens identified to date are high molecular weight proteins rich in coiled-coil domains and localized to the cytoplasmic face of the Golgi cisternae. The characteristic features of these Golgi autoantigens are interestingly similar to selected human autoantigens reported in other intracellular compartments such as endosome, centrosome, and centromere. The implication of this class of autoantigens in autoimmunity is discussed.


Citations per Year

52 Citations

Semantic Scholar estimates that this publication has 52 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@article{Nozawa2005UniqueAS, title={Unique and shared features of Golgi complex autoantigens.}, author={Kazuhisa Nozawa and Marvin J. Fritzler and Edward K L Chan}, journal={Autoimmunity reviews}, year={2005}, volume={4 1}, pages={35-41} }