Unique Regulatory Mechanisms for the Human Embryonic Stem Cell Cycle.

  title={Unique Regulatory Mechanisms for the Human Embryonic Stem Cell Cycle.},
  author={Jennifer J. VanOudenhove and Rodrigo A Grandy and Prachi N Ghule and Jane B Lian and Janet L Stein and Sayyed K Zaidi and Gary S Stein},
  journal={Journal of cellular physiology},
  volume={232 6},
The cell cycle in pluripotent human embryonic stem cells is governed by unique mechanisms that support unrestricted proliferation and competency for endodermal, mesodermal, and ectodermal differentiation. The abbreviated G1 period with retention of uncompromised fidelity for genetic and epigenetic mechanisms operative in control of proliferation support competency for expansion of the pluripotent cell population that is fundamental for initial stages of development. Regulatory events during the… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 5 times over the past 90 days. VIEW TWEETS

From This Paper

Topics from this paper.
1 Citations
0 References
Similar Papers

Similar Papers

Loading similar papers…