Uniparental inheritance of organelle genes

  title={Uniparental inheritance of organelle genes},
  author={C. William Birky},
  journal={Current Biology},
  • C. Birky
  • Published 26 August 2008
  • Biology
  • Current Biology

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The inheritance of genes in mitochondria and chloroplasts: laws, mechanisms, and models.
  • C. Birky
  • Biology
    Annual review of genetics
  • 2001
The inheritance of mitochondrial and chloroplast genes differs from that of nuclear genes in showing vegetative segregation, uniparental inheritance, intracellular selection, and reduced
The inheritance of organelle genes and genomes: patterns and mechanisms.
The recent observation of a sex-determining gene in the basidiomycete yeast Cryptococcus neoformans, which controls mitochondrial DNA inheritance, has opened up potentially exciting research opportunities for identifying specific molecular genetic pathways that control organelle inheritance.
A broad survey of recombination in animal mitochondria.
A survey of 279 animal mtDNA data sets shows that there is widespread evidence of recombination; for one test as many as 14.2% of the data sets reject a model of clonal inheritance and in several data sets, including primates, the recombinants can be identified visually.
A reanalysis of the indirect evidence for recombination in human mitochondrial DNA
The results suggest a lack of evidence for recombination in human mtDNA, and the relationship between linkage disequilibrium (LD) and distance between sites under a variety of conditions using two measures of LD, r2 and ∣D′∣.
Deleterious mutation accumulation in organelle genomes
The authors' results suggest an almost universal increase in the fixation probabilities of mildly deleterious mutations arising in mitochondrial and chloroplast genomes relative to those arising in the recombining nuclear genome.
Biological Sciences West
  • Biological Sciences West
E-mail: birky@u.arizona
  • E-mail: birky@u.arizona