Union is strength: matrix elasticity and microenvironmental factors codetermine stem cell differentiation fate

Abstract

Stem cells are an attractive cellular source for regenerative medicine and tissue engineering applications due to their multipotency. Although the elasticity of the extracellular matrix (ECM) has been shown to have crucial impacts in directing stem cell differentiation, it is not the only contributing factor. Many researchers have recently attempted to… (More)
DOI: 10.1007/s00441-015-2190-z

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