Uninephrectomy reduces apoptotic cell death and enhances renal tubular cell regeneration in ischemic ARF in rats.

@article{Nakajima1996UninephrectomyRA,
  title={Uninephrectomy reduces apoptotic cell death and enhances renal tubular cell regeneration in ischemic ARF in rats.},
  author={Tamie Nakajima and Takehiko Miyaji and Akihiko Kawaguchil yoshihiro Kato and Naoki Ikegaya and Tadashi Yamamoto and Akira Hishida},
  journal={The American journal of physiology},
  year={1996},
  volume={271 4 Pt 2},
  pages={F846-53}
}
Contralateral uninephrectomy attenuates unilateral ischemic renal injury functionally and morphologically. In this study we investigated the effects of uninephrectomy on apoptotic renal cell death and tubular regeneration in ischemic acute renal failure (ARF) in rats. Unilateral ischemic injury was provoked by a 60-min left renal artery occlusion in right-nephrectomized (Nx) and sham-nephrectomized (sham-Nx) rats. Uninephrectomy attenuated tubular damage 48 h following the renal ischemia… CONTINUE READING