Unimpaired autoreactive T-cell traffic within the central nervous system during tumor necrosis factor receptor-mediated inhibition of experimental autoimmune encephalomyelitis.

Abstract

The critical role of tumor necrosis factor (TNF) as a mediator in autoimmune inflammatory processes is evident from in vivo studies with TNF-blocking agents. However, the mechanisms by which TNF, and possibly also its homologue lymphotoxin alpha, contributes to development of pathology in rheumatoid arthritis and Crohn disease and in animal models like… (More)

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@article{Krner1995UnimpairedAT, title={Unimpaired autoreactive T-cell traffic within the central nervous system during tumor necrosis factor receptor-mediated inhibition of experimental autoimmune encephalomyelitis.}, author={Heinrich K{\"{o}rner and Anna Goodsall and Frances A. Lemckert and Bernard J. Scallon and John Ghrayeb and Andrew L. Ford and Jonathon D. Sedgwick}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={1995}, volume={92 24}, pages={11066-70} }