Unilateral striatal dopamine depletion: time-dependent effects on cortical function and behavioural correlates.

@article{Steiner2001UnilateralSD,
  title={Unilateral striatal dopamine depletion: time-dependent effects on cortical function and behavioural correlates.},
  author={Hermann-J. Steiner and Stephen T. Kitai},
  journal={The European journal of neuroscience},
  year={2001},
  volume={14 8},
  pages={
          1390-404
        }
}
Previously, we showed that unilateral blockade of D1 dopamine receptors in the striatum inhibits immediate-early gene expression bilaterally throughout large parts of the cortex, including sensory-evoked expression in the barrel cortex. To further investigate this dopamine regulation of cortical function, we examined the effects of dopamine depletion on cortical gene regulation and behavioural correlates. Two days after unilateral infusion of 6-hydroxydopamine into the midbrain, rats displayed… CONTINUE READING
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