Unilateral lesion of the nigrostriatal pathway decreases the response of GABA interneurons in the dorsal raphe nucleus to 5-HT(1A) receptor stimulation in the rat.

Abstract

This study examined the firing rate and pattern of electrophysiologically and chemically identified GABA interneurons in the dorsal raphe nucleus (DRN), and role of 5-HT(1A) receptor agonist 8-OH-DPAT and the medial prefrontal cortex (mPFC) in the firing activity in rats with 6-hydroxydopamine lesions of the substantia nigra pars compacta (SNc). The… (More)
DOI: 10.1016/j.neuint.2012.09.012

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@article{Hou2012UnilateralLO, title={Unilateral lesion of the nigrostriatal pathway decreases the response of GABA interneurons in the dorsal raphe nucleus to 5-HT(1A) receptor stimulation in the rat.}, author={Cai Qin Hou and Li Xue and Jin Feng and L Zhang and Y Wang and Liying Chen and Tianyun Wang and Qinglin Zhang and J Liu}, journal={Neurochemistry international}, year={2012}, volume={61 8}, pages={1344-56} }