Unilateral inactivation of the basolateral amygdala attenuates context-induced renewal of Pavlovian-conditioned alcohol-seeking.

@article{Chaudhri2013UnilateralIO,
  title={Unilateral inactivation of the basolateral amygdala attenuates context-induced renewal of Pavlovian-conditioned alcohol-seeking.},
  author={Nadia Chaudhri and Catherine A. Woods and Lacey L. Sahuque and Thomas M. Gill and Patricia H Janak},
  journal={The European journal of neuroscience},
  year={2013},
  volume={38 5},
  pages={
          2751-61
        }
}
Environmental contexts associated with drug use promote craving in humans and drug-seeking in animals. We hypothesized that the basolateral amygdala (BLA) itself as well as serial connectivity between the BLA and nucleus accumbens core (NAC core) were required for context-induced renewal of Pavlovian-conditioned alcohol-seeking. Male Long-Evans rats were trained to discriminate between two conditioned stimuli (CS): a CS+ that was paired with ethanol (EtOH, 20%, v/v) delivery into a fluid port… CONTINUE READING
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