Unilateral frontal lobe contusion and forelimb function: chronic quantitative and qualitative impairments in reflexive and skilled forelimb movements in rats.

@article{Whishaw2004UnilateralFL,
  title={Unilateral frontal lobe contusion and forelimb function: chronic quantitative and qualitative impairments in reflexive and skilled forelimb movements in rats.},
  author={Ian Q. Whishaw and Dionne M. Piecharka and Fiona D. Zeeb and Donald G. Stein},
  journal={Journal of neurotrauma},
  year={2004},
  volume={21 11},
  pages={1584-600}
}
Traumatic brain injury induced by mechanical impacts of the head can be modeled in rats in order to investigate acute and chronic therapy. Because frontal lobe contusion affects the neural representation of the forelimb in both the neocortex and basal ganglia, the purpose of the present experiments was to examine the chronic changes in reflexive and skilled forelimb induced by the injury. Contusions produced a cavity in the sensorimotor cortex, accompanied by shrinkage of the pyramidal tract… CONTINUE READING
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