Unilateral amyloid-beta25-35 injection into the rat amygdala increases the expressions of aberrant tau phosphorylation kinases.

@article{Huang2010UnilateralAI,
  title={Unilateral amyloid-beta25-35 injection into the rat amygdala increases the expressions of aberrant tau phosphorylation kinases.},
  author={Jing Huang and Yu-Juan Chen and Wei-hong Bian and Jing Yu and Yu-wu Zhao and Xueyuan Liu},
  journal={Chinese medical journal},
  year={2010},
  volume={123 10},
  pages={1311-4}
}
BACKGROUND Neuropathologically, Alzheimer disease (AD) is characterized by the presence of extracellular plaques enriched in beta-amyloid peptides; however, the mechanism by which it results in the neurotoxicity is uncertain. The purpose of this study was to investigate whether it would prompt the progress of Alzheimer disease via enhancement of aberrant phosphorylated tau that results from its increased kinase gene expression. METHODS Twenty-four male rats were divided into three groups, and… CONTINUE READING