Unified synthesis of tirandamycins and streptolydigins.

@article{Yoshimura2015UnifiedSO,
  title={Unified synthesis of tirandamycins and streptolydigins.},
  author={Hikaru Yoshimura and Keisuke Takahashi and J. Ishihara and S. Hatakeyama},
  journal={Chemical communications},
  year={2015},
  volume={51 95},
  pages={
          17004-7
        }
}
The asymmetric total syntheses of tirandamycins A-D and tirandalydigin as well as the synthesis of the left-hand fragment of streptolydiginone and streptolydigin from a common intermediate are described. The comprehensive approach features the highly enantio- and diastereoselective assembly of the anti,anti,syn-stereotetrad unit which relies on a cinchona alkaloid-catalyzed asymmetric Morita-Baylis-Hillman reaction. 
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