Unified prebiotically plausible synthesis of pyrimidine and purine RNA ribonucleotides

@article{Becker2019UnifiedPP,
  title={Unified prebiotically plausible synthesis of pyrimidine and purine RNA ribonucleotides},
  author={S. Becker and Jonas Feldmann and Stefan Wiedemann and Hidenori Okamura and Christina Schneider and K. Iwan and Antony Crisp and M. Rossa and Tynchtyk Amatov and T. Carell},
  journal={Science},
  year={2019},
  volume={366},
  pages={76 - 82}
}
Conditions right for making nucleosides In the absence of biological catalysts and metabolism, can atmospheric and geochemical processes provide the substrates and conditions required for production of biological molecules? Becker et al. devised an abiotic synthetic scheme that allows for accumulation of both purine and pyrimidine nucleoside mono- and diphosphates (see the Perspective by Hud and Fialho). A key starting material for this chemistry, hydroxylamine and/or hydroxylamine disulfonate… Expand
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