Unified parasite lactate dehydrogenase and histidine-rich protein ELISA for quantification of Plasmodium falciparum.

@article{Martin2009UnifiedPL,
  title={Unified parasite lactate dehydrogenase and histidine-rich protein ELISA for quantification of Plasmodium falciparum.},
  author={Samuel K. Martin and G R Rajasekariah and George Awinda and John N Waitumbi and Carolyne M Kifude},
  journal={The American journal of tropical medicine and hygiene},
  year={2009},
  volume={80 4},
  pages={
          516-22
        }
}
There is a need for more objective and quantitative tools to replace microscopy in malaria diagnosis. Emphasis has recently been placed on alternative methods such as immunochromatography-based rapid tests. However, these tests provide only qualitative results. Two bio-molecules, parasite lactate dehydrogenase (pLDH) and histidine-rich proteins (HRPs), that are released by the intra-erythrocytic stages of the parasite offer certain specific characteristics that could potentially improve malaria… CONTINUE READING

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