Unified biomimetic assembly of voacalgine A and bipleiophylline via divergent oxidative couplings.


Bipleiophylline is a highly complex monoterpene indole alkaloid composed of two pleiocarpamine units anchored on an aromatic spacer platform. The synthesis of bipleiophylline is considered as a mountain to climb by the organic chemistry community. Here, a unified oxidative coupling protocol between indole derivatives and 2,3-dihydroxybenzoic acid, mediated… (More)
DOI: 10.1038/nchem.2735


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