Unidirectional water absorption as a measure of intestinal surface area in rats.

@article{Fiedorek1991UnidirectionalWA,
  title={Unidirectional water absorption as a measure of intestinal surface area in rats.},
  author={S C Fiedorek and William J. Klish and David Y Graham},
  journal={Journal of pediatric gastroenterology and nutrition},
  year={1991},
  volume={12 2},
  pages={237-42}
}
Methods to measure expeditiously the anatomic and functional mucosal surface area of the small intestine are needed. We postulated that passive, unidirectional water flux would assess the anatomic mucosal surface area and that the increase in unidirectional flux that occurs in the presence of glucose would correlate with functional surface area. These hypotheses were tested in control and methotrexate-treated rats. A single-pass perfusion technique was used in vivo. Methotrexate treatment… CONTINUE READING

From This Paper

Topics from this paper.
1 Citations
0 References
Similar Papers

Similar Papers

Loading similar papers…