Unidentified bright objects in neurofibromatosis type 1: conventional MRI in the follow-up and correlation of microstructural lesions on diffusion tensor images.

@article{FerrazFilho2012UnidentifiedBO,
  title={Unidentified bright objects in neurofibromatosis type 1: conventional MRI in the follow-up and correlation of microstructural lesions on diffusion tensor images.},
  author={Jos{\'e} Roberto Lopes Ferraz-Filho and Ant{\^o}nio Jos{\'e} da Rocha and Marcos Pontes Muniz and Ant{\^o}nio Soares de Souza and Eny Maria Goloni-Bertollo and Erika Cristina Pavarino-Bertelli},
  journal={European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society},
  year={2012},
  volume={16 1},
  pages={42-7}
}
PURPOSE To evaluate the evolution of unidentified bright objects (UBOs) in individuals with neurofibromatosis type 1 (NF1) by serial magnetic resonance imaging (MRI), and to relate this to regional fractional anisotropy (FA). MATERIALS AND METHODS The signal pattern of the T2-weighted sequences in the basal ganglia, thalamus, brain stem, and cerebellum for 27 NF1 individuals and a control group were analyzed by diffusion tensor imaging (DTI). The presence or absence of UBOs in 2 consecutive… CONTINUE READING
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