Unfolded protein response-related gene regulation in inflamed periodontal tissues with and without Russell bodies.

@article{Seo2016UnfoldedPR,
  title={Unfolded protein response-related gene regulation in inflamed periodontal tissues with and without Russell bodies.},
  author={Benedict Seo and D E Coates and Gregory John Seymour and Alison M Rich},
  journal={Archives of oral biology},
  year={2016},
  volume={69},
  pages={1-6}
}
OBJECTIVE To examine the expression of unfolded protein response (UPR) genes, a set of genes that are activated to assist in protein trafficking and cellular homeostasis when endoplasmic reticulum (ER) stress occurs, in inflamed and uninflamed periodontal tissues, with or without Russell bodies (RB). RB are a histologically apparent extension of the ER that represents an accumulation of abnormal proteins that cannot be secreted or degraded and may serve as a marker of ER stress. DESIGN… CONTINUE READING