Unexpected late rise in plasma acetaminophen concentrations with change in risk stratification in acute acetaminophen overdoses.

@article{Dougherty2012UnexpectedLR,
  title={Unexpected late rise in plasma acetaminophen concentrations with change in risk stratification in acute acetaminophen overdoses.},
  author={Patrick P. Dougherty and Wendy Klein-Schwartz},
  journal={The Journal of emergency medicine},
  year={2012},
  volume={43 1},
  pages={58-63}
}
BACKGROUND The acetaminophen risk analysis nomogram is used to predict hepatotoxicity risk in acute acetaminophen overdose based on a single plasma acetaminophen concentration (PAC) measured between 4 and 24 h after ingestion. There are case reports of patients with acute overdoses of acetaminophen combination products in whom a toxic PAC occurred later after an initial non-toxic PAC at approximately 4 h. OBJECTIVES The objective was to describe patients who had an initial non-toxic PAC and a… CONTINUE READING
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