Unexpected increased ferritin concentration in patients with anorexia nervosa

@article{Tran2013UnexpectedIF,
  title={Unexpected increased ferritin concentration in patients with anorexia nervosa},
  author={Jimmy N. Tran and Colin Story and David J. Moore and Michael Patrick Metz},
  journal={Annals of Clinical Biochemistry},
  year={2013},
  volume={50},
  pages={504 - 506}
}
stage and we encourage others to validate the new formula in different population samples. However, clinical validity and utility studies are of additional importance, as it is necessary to evaluate an eventual improvement of therapeutic management and costeffectiveness of a new approach. A study evaluating the performance of the new formula compared to beta-quantification in a sample of a clinically welldefined cohort is also needed. 

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References

SHOWING 1-10 OF 12 REFERENCES
Iron status and haematological changes in adolescent female inpatients with anorexia nervosa
TLDR
Investigation of the incidence of iron deficiency (both latent iron deficiency and iron deficiency anaemia) in post menarchal female adolescent patients hospitalized with anorexia nervosa and changes in iron status during refeeding.
Iron metabolism in patients with anorexia nervosa: elevated serum hepcidin concentrations in the absence of inflammation.
TLDR
Hematologic variables and markers of iron status, including serum hepcidin, were measured before and after nutritional rehabilitation, and Hepcidin and ferritin concentrations were higher in the serum of AN patients, without any evidence of iron overload or inflammation.
Extreme hyperferritinaemia; clinical causes
TLDR
An audit study found that extreme hyperferritinaemia was rare with only 0.08% of ferritin requests displaying this and the main causes included multiple blood transfusions, malignant disease, hepatic disease and suspected Still's disease.
Functional hypothalamic amenorrhoea: a partial and reversible gonadotrophin deficiency of nutritional origin
TLDR
Assessment in women with FHA and normal body mass index (BMI) and apparently normal daily activities, the degree of impairment of GnRH secretion, its nutritional origin and its reversibility is assessed.
Indicators of nutritional status in restricting-type anorexia nervosa patients: a 1-year follow-up study.
TLDR
The changes in transferrin, C3 and C4 levels during the out-patient treatment reveal an increased risk of relapses after 1 year since hospital admission.
Haematological changes and iron status in teenage girls with eating disorders and weight loss—the importance of menstrual status
TLDR
The objective is to study haematological changes and iron stores in teenage girls with eating disorders and weight loss to find out if these changes are related to weight loss and eating disorders.
Nutritional status in anorexia nervosa: clinical chemistry, vitamins, iron and zinc.
TLDR
The results obtained did not indicate an inadequate status of vitamins, iron and zinc in patients with AN, and the status parameters of thiamin, vitamin B6, vitamin C, folate, vitamin E and vitamin D were not significantly different.
Serum ferritin: Past, present and future.
TLDR
The role of serum ferritin in physiological and pathological processes and its use as a clinical tool is discussed, including newly described roles in iron delivery, angiogenesis, inflammation, immunity, signaling and cancer.
The clinical biochemistry of anorexia nervosa
  • A. Winston
  • Medicine
    Annals of clinical biochemistry
  • 2012
TLDR
In anorexia nervosa, under-nutrition and weight regulatory behaviours such as vomiting and laxative abuse can lead to a range of biochemical problems, which may produce electrolyte abnormalities, hyper- and hypoglycaemia, acuteThiamin depletion and fluid balance disturbance; careful biochemical monitoring and thiamin replacement are therefore essential during refeeding.
Hyperferritinaemia; laboratory implications
  • M. Crook
  • Medicine
    Annals of clinical biochemistry
  • 2012
TLDR
Two novel mutations in the L-ferritin coding sequence associated with benign hyperferritinaemia showing abnormal ferritin glycosylation are described, which are suggested to be an independent indicator of poor glycaemic control in type 2 diabetes mellitus.
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