Unexpected enzyme-catalyzed regioselective acylation of flavonoid aglycones and rapid product screening.

@article{Kyriakou2012UnexpectedER,
  title={Unexpected enzyme-catalyzed regioselective acylation of flavonoid aglycones and rapid product screening.},
  author={Eleni Kyriakou and Alexandra Primikyri and Pantelis Charisiadis and Maria H. Katsoura and Ioannis P. Gerothanassis and Haralambos Stamatis and Andreas G Tzakos},
  journal={Organic & biomolecular chemistry},
  year={2012},
  volume={10 9},
  pages={
          1739-42
        }
}
Unprecedented regioselective acylation of flavonoid aglycones was achieved using Candida antarctica lipase B (CALB). The rapid screening of product formation was performed by the use of the high resolution phenol-type OH (1)H NMR spectral region recorded after the addition of picric acid. 

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