Unexpected diversity displayed in cDNAs expressed by the immune cells of the purple sea urchin, Strongylocentrotus purpuratus.

@article{Terwilliger2006UnexpectedDD,
  title={Unexpected diversity displayed in cDNAs expressed by the immune cells of the purple sea urchin, Strongylocentrotus purpuratus.},
  author={David P. Terwilliger and Katherine M. Buckley and Dhruti P. Mehta and Priya G. Moorjani and L Courtney Smith},
  journal={Physiological genomics},
  year={2006},
  volume={26 2},
  pages={134-44}
}
We recently identified a unique family of transcripts, the 185/333 family, that comprise approximately 60% of the mRNAs induced by coelomocytes from the purple sea urchin in response to immunological challenge from lipopolysaccharide. An analysis of 81 full-length cDNAs revealed 67 unique nucleotide sequences encoding 64 different proteins. Diversity of the transcripts was based on 25 sequence blocks, or "elements," which resulted in 22 different element patterns based on their presence or… CONTINUE READING

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