Undifferentiated spondyloarthropathies in Brazilians: importance of HLA-B27 and the B7-CREG alleles in characterization and disease progression.

@article{SampaioBarros2003UndifferentiatedSI,
  title={Undifferentiated spondyloarthropathies in Brazilians: importance of HLA-B27 and the B7-CREG alleles in characterization and disease progression.},
  author={Percival D Sampaio-Barros and Roseneide Aparecida Conde and Eduardo Ant{\^o}nio Donadi and Maria Helena Stangler Kraemer and L{\'i}gia Beatriz Lopes Persoli and Ibsen Bellini Coimbra and L{\'i}lian Teresa Lavras Costallat and Adil Muhib S{\^a}mara and Manoel Barros B{\'e}rtolo},
  journal={The Journal of rheumatology},
  year={2003},
  volume={30 12},
  pages={2632-7}
}
OBJECTIVE To analyze the profile of the HLA-B27 and B7 cross-reactive group (CREG) alleles and the role of these markers in disease characterization and progression in patients with undifferentiated spondyloarthropathies (uSpA). METHODS A total of 80 patients with a diagnosis of uSpA (40 HLA-B27 positive and 40 HLA-B27 negative) were prospectively studied for 2 years. The control group consisted of 66 HLA-B27 positive and 112 HLA-B27 negative individuals without a history of seronegative SpA… CONTINUE READING
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