Undifferentiated Neuroblastoma Cells Are More Sensitive to Photogenerated Oxidative Stress Than Differentiated Cells.

Abstract

Neuroblastoma is one of the most aggressive cancers and has a complex form of differentiation. We hypothesized that advanced cellular differentiation may alter the susceptibility of neuroblastoma to photodynamic treatment (PDT) and confer selective survival advantage. We demonstrated that hematoporphyrin uptake by undifferentiated SH-SY5Y cells was lower… (More)
DOI: 10.1002/jcb.25165

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Cite this paper

@article{Lee2015UndifferentiatedNC, title={Undifferentiated Neuroblastoma Cells Are More Sensitive to Photogenerated Oxidative Stress Than Differentiated Cells.}, author={Chu-I Lee and Jing-Huei Perng and Huang-Yo Chen and Yi-Ren Hong and Jyh-Jye Wang}, journal={Journal of cellular biochemistry}, year={2015}, volume={116 9}, pages={2074-85} }